With propolis & myrrh. Contains Xylitol to help prevent plaque and propolis and myrrh for a healthy feeling mouth. We use natural ingredients in innovative ways without adding anything artificial. This product does not contain saccharin; artificial sweeteners, preservatives, colors, or flavors; or animal ingredients. Tom's of Maine products are tested for safety without the use of animals. Fluoride Free-Some people do not want fluoride in their toothpaste. We produce this toothpaste because we respect our customers' diverse needs and interests. What is Xylitol? Xylitol, a natural ingredient derived from birch trees, helps to prevent plaque buildup. What are Propolis and Myrrh? We use two special herbal resins, propolis and myrrh, to promote a clean, healthy feeling mouth. Propolis is a mixture of tree resin gathered by bees and myrrh resin comes from the myrrh bush. Made in U.S.A.